Encapsulated Booklet
Encapsulated booklets are ideal for pharmaceutical products that demand secure, high-capacity labeling in tightly regulated environments. Designed for clinical trials, hospital use and commercial supply chains, these labels combine a multi-page format with a protective outer layer to keep critical information intact, legible and compliant.
Encapsulated Booklet Labels for Secure Pharmaceutical Packaging
An encapsulated booklet label is a specialized type of expanded content label (ECL) that houses a fold-out booklet inside a sealed, durable label format. This construction protects the content from moisture, abrasion and handling, making it ideal for demanding environments.
This packaging type:
- Consolidates prescribing information, usage guidelines and multilingual inserts into a single label
- Seamlessly integrates with high-speed labeling lines
- Reduces packaging complexity by eliminating the need for secondary packaging or separate leaflets
- Supports compliance across global markets with regulation-ready labeling
Key Features of Encapsulated Booklets
We’ve purposefully designed every detail of our encapsulated booklet labels to support complex product requirements. They enhance usability and regulatory confidence with these key features:
- Design flexibility: Custom formats — such as fold-out, glued and stitched — accommodate a variety of product packaging and label real estate. Their flexibility lets you tailor the label to any container shape or size, so you will not have to redesign your packaging or sacrifice brand consistency.
- Intuitive layout: The user-friendly design makes it easy for patients, providers and clinical staff to access critical information quickly, without compromising the label’s integrity.
- Encapsulation: The overlaminate protects the booklet inside a sealed layer. Your content stays secure, clean, and legible throughout shipping, storage, and end-use.
- Multi-page format: These booklets can hold a large amount of content, so you can meet global regulatory requirements, include multiple languages and provide full instructions — all in one compact label.
- Secure design: Made to perform under pressure, they withstand handling and storage, minimizing rework and label damage.
Why Choose CCL Healthcare for Expanded Content Labels?
With nearly 75 years of experience and dozens of cGMP compliant healthcare facilities worldwide, CCL Healthcare is a global leader in custom-printed packaging solutions. Our unmatched portfolio of expanded content labels is backed by expert engineering support, and our product specialists work in close collaboration with your team to ensure every label fits your exact needs.
We combine global production power with localized support to meet tight deadlines and regional regulations. From tamper-evident features to smart label integrations, we bring innovation to every solution we deliver.
Tailor Your Labels With These ECL Options
Booklets
- Stitched Booklets: 4-184 pages
- Glue-Bound Booklets: 4-48 pages
Leaflets
- Single Panel Max: 16 panels
- Multiple Ribbon Glue-Bound Max: 32 panels
Removable
Removable ECL leaflets allow the booklet to detach information without damaging the rest of the package.
Resealable
Resealable ECL leaflets can open and close repeatedly without damage, feature optional dirt-repellent lamination and come in various closure styles for easy, hygienic reuse.
Base Construction
- Full-base ECL: Full-base labels are designed for flat packaging surfaces like cartons, kits and cards. The base extends edge-to-edge beneath the ECL and is available in black, opaque, white, clear or metalized materials.
- Partial-base ECL: Perfect for cylindrical packaging, partial-base labels attach securely to containers such as bottles, vials, canisters and syringes. The design allows the label to wrap around the container’s curve and fasten neatly using a secondary tab, maintaining form and function. Choose from white, clear, black, opaque or metalized finishes.
- Segmented-base ECL: For packaging that requires ECLs to span corners or wrap around edges, segmented bases provide flexibility and stability. Featuring a dual-base section, this construction supports a snug fit even around tight angles, which is critical for specialty cartons or boxes.
Other Available ECL Formats
- Back Label with Stitched Booklet
- Full Graphics OTC with ECL
- Multi-Wrap
- Back Label with Glue-Bound Booklet
- Tear-Off Leaflet with Zipper Opening
- Clinical Booklets
- Back Label with Leaflet
- Encapsulated Tear-Off Leaflet
Available Imprinting Methods
- Hot stamp
- Data lase
- Laser
- Thermal transfer
Lamination Options
- Patterned lamination for imprinting: This technique leaves specific areas unlaminated, making room for variable printing
- Fully laminated ECL: With complete lamination from edge to edge, these labels offer comprehensive protection from moisture, abrasion and handling
Compatible Container Types
ECLs can be tailored to fit various packaging types, whether they are flat, curved or irregularly shaped:
- Carton
- Auto injector
- Vial
- Syringe
- Round bottle
- Ampule
- Square bottle
Expanded Content Label Options
Booklets
- Stitched booklets: 4-184 pages
- Glued bound booklets: 4-48 pages
Leaflets
- Single Panel max: 16 panels
- Multiple Ribbon glue bound max: 32 panels
- Removable ECL leaflets allow the booklet to detach information without damaging the rest of the package.
- Resealable ECL Leaflets allow the label to be opened and closed for repeated use. The leaflet label also has a resealable closure available in many different versions. It can be covered with a dirt repellent and attractive looking lamination.
Tab opening direction options: left or right
Tab opening direction options: left or right
Tab opening direction options: left or right
Tab opening direction options: left or right
Full Base Label -Expanded Content Labels
Full Base Labels are designed for use on flat surfaces including cartons, kits and cards. The base spans the entire length of the ECL from edge to edge. Bases can be constructed from a large array materials and is offered Clear, White, Black, Opaque or metalized substrates.
Full Base Section Shown in Blue
Front Side of the Label
Partial Base Label -Expanded Content Labels
Partial Base Labels are designed for use with cylindrical clinical containers such as bottles, vials, canisters and syringes. Partial Bases are a small section of base that adheres to the container and allows the booklet to wrap around the curved surface, generally the tab section is used to adhere to the other side of the container, securing the booklet. Bases can be constructed from a large array materials and is offered Clear, White, Black, Opaque or metalized substrates.
Small Partial Base Section Shown in Blue
Large Partial Base shown in Blue
Front Side of the Label
Segmented Label Base Construction -Expanded Content Labels
Segmented label base constructions are used when it is necessary to wrap a booklet label around one or more edges of a box or carton. As illustrated below it uses “2 base section” so the label is able to bend and adhere correctly around corners or tight radiuses. It is important to have all the packaging component dimensions when designing this type of label.
2-Base Section Shown in Blue
Front Side of the Label
- Full Graphics OTC with ECL
- Multi-Wrap
- Encapsulated Tear off leaflet
- Back label with leaflet
- Back label with stitched booklet
- Back label with glue bound booklet
- Tear off leaflet with zipper opening
- Clinical Booklets
- Thermal transfer
- Laser
- Hot stamp
- Data lase
Patterned Lamination for Imprinting
Patterned Lamination leaves an unlamented area for Imprinting.
Label Example
Fully Laminated - ECL
Full Lamination shown in pink
Label Example
ECL’s can be custom made for many types of packaging. The flexibility of ECL’s designs even allow the most difficult containers or primary package to accommodate an ECL.
- Round Bottle
- Square Bottle
- Vial
- Syringe
- Ampule
- Carton
- Auto Injector
- and More
ECL Questions?
Not sure of what you need for your application ? One of our packaging specialists will be glad to help.
Simplify Labeling With One Consolidated Booklet
When space is limited and precision is critical, encapsulated booklet labels offer the protection, compliance and flexibility your pharmaceutical products demand. Whether you’re managing clinical trials or preparing for global distribution, our team can help you find the right solution.
Contact us today to speak with a labeling expert or request a custom quote.
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