Encapsulated Leaflets
Expanded Content Labels
Encapsulated leaflet labels are multi-panel labels that deliver extended content in a compact format. These labels house critical information, such as dosage instructions, regulatory data and multilingual content, without expanding a product’s footprint, making them ideal for pharmaceutical and clinical applications. Their durable, protective design ensures clarity and integrity from packaging through end-use.
Why Encapsulated Leaflets?
Encapsulated leaflets are a form of expanded content labels (ECLs) that offer an efficient, space-saving solution. They’re perfect for regulated industries like pharmaceuticals, clinical trials and medical devices where space is limited but compliance is critical. They help you:
- Optimize space without sacrificing content:Â Deliver detailed instructions, multilingual content and clinical trial data without increasing the size of your primary packaging. These leaflets are ideal for small containers such as vials, kits and syringes.
- Improve readability and access:Â Design labels to open cleanly and intuitively, helping patients, clinicians and pharmacists access critical content without tearing or damaging the container.
- Withstand tough handling conditions:Â Protect essential printed information from moisture, friction, and repeated handling in cold chain logistics, field use, or high-volume distribution.
- Safeguard product integrity:Â Prevent tampering and contamination with encapsulated protection that resists dirt, abrasion and unauthorized opening.
- Customize for your process:Â Choose from various base constructions, resealable closures and finish options. Add features like QR codes, barcodes or variable data to streamline inventory management, traceability or patient engagement.
- Stay ahead of compliance requirements:Â Meet evolving global labeling standards with labels designed to deliver all required content in a single, cGMP-ready format.
ECL Options to Customize Your Leaflets
Booklets
- Stitched booklets:Â 4-184 pages
- Glue-bound booklets:Â 4-48 pages
Leaflets
- Single panel max:Â 16 panels
- Multiple ribbon glue-bound max:Â 32 panels
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Removable
Removable ECLÂ leaflets allow the booklet to detach information without damaging the rest of the package.
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Resealable
Resealable ECL leaflets are designed for repeated use without wear. They’re available in various closure styles and can be finished with dirt-resistant, cleanable lamination to support hygiene and durability.
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Base Construction
- Full-base ECL: Full-base labels are designed for flat packaging surfaces like cartons, kits and cards. The base extends edge-to-edge beneath the ECL and is available in black, opaque, white, clear or metalized materials.
- Partial-base ECL: Perfect for cylindrical packaging, partial-base labels attach securely to containers such as bottles, vials, canisters and syringes. The design allows the label to wrap around the container’s curve and fasten neatly using a secondary tab, maintaining form and function. Choose from white, clear, black, opaque or metalized finishes.
- Segmented-base ECL:Â For packaging that requires ECLs to span corners or wrap around edges, segmented bases provide flexibility and stability. Featuring a dual-base section, this construction supports a snug fit even around tight angles, which is critical for specialty cartons or boxes.
Other Available ECL Formats
- Back Label with Stitched Booklet
- Full Graphics OTC with ECL
- Multi-Wrap
- Back Label with Glue-Bound Booklet
- Tear-Off Leaflet with Zipper Opening
- Clinical BookletsÂ
- Back Label with Leaflet
- Encapsulated Tear-Off Leaflet
Available Imprinting Methods
- Hot stamp
- Data lase
- Laser
- Thermal transfer
Lamination Options
- Patterned lamination for imprinting:Â This technique leaves specific areas unlaminated, making room for variable printing
- Fully laminated ECL:Â With complete lamination from edge to edge, these labels offer comprehensive protection from moisture, abrasion and handling
Compatible Container Types
ECLs can be tailored to fit various packaging types, whether they are flat, curved or irregularly shaped:
- Carton
- Auto injectorÂ
- Vial
- Syringe
- Round bottle
- Ampule
- Square bottle
Expanded Content Label Options
Booklets
- Stitched booklets: 4-184 pages
- Glued bound booklets: 4-48 pages
Leaflets
- Single Panel max: 16 panels
- Multiple Ribbon glue bound max: 32 panels
- Removable ECL leaflets allow the booklet to detach information without damaging the rest of the package.
- Resealable ECL Leaflets allow the label to be opened and closed for repeated use. The leaflet label also has a resealable closure available in many different versions. It can be covered with a dirt repellent and attractive looking lamination.
Tab opening direction options: left or right
Tab opening direction options: left or right
Tab opening direction options: left or right
Tab opening direction options: left or right
Full Base Label -Expanded Content Labels
Full Base Labels are designed for use on flat surfaces including cartons, kits and cards. The base spans the entire length of the ECL from edge to edge. Bases can be constructed from a large array materials and is offered Clear, White, Black, Opaque or metalized substrates.
Full Base Section Shown in Blue
Front Side of the Label
Partial Base Label -Expanded Content Labels
Partial Base Labels are designed for use with cylindrical clinical containers such as bottles, vials, canisters and syringes. Partial Bases are a small section of base that adheres to the container and allows the booklet to wrap around the curved surface, generally the tab section is used to adhere to the other side of the container, securing the booklet. Bases can be constructed from a large array materials and is offered Clear, White, Black, Opaque or metalized substrates.
Small Partial Base Section Shown in Blue
Large Partial Base shown in Blue
Front Side of the Label
Segmented Label Base Construction -Expanded Content Labels
Segmented label base constructions are used when it is necessary to wrap a booklet label around one or more edges of a box or carton. As illustrated below it uses “2 base section” so the label is able to bend and adhere correctly around corners or tight radiuses. It is important to have all the packaging component dimensions when designing this type of label.
2-Base Section Shown in Blue
Front Side of the Label
- Full Graphics OTC with ECL
- Multi-Wrap
- Encapsulated Tear off leaflet
- Back label with leaflet
- Back label with stitched booklet
- Back label with glue bound booklet
- Tear off leaflet with zipper opening
- Clinical BookletsÂ
- Thermal transfer
- Laser
- Hot stamp
- Data lase
Patterned Lamination for Imprinting
Patterned Lamination leaves an unlamented area for Imprinting.
Label Example
Fully Laminated - ECL
Full Lamination shown in pink
Label Example
ECL’s can be custom made for many types of packaging. The flexibility of ECL’s designs even allow the most difficult containers or primary package to accommodate an ECL.
- Round Bottle
- Square Bottle
- Vial
- Syringe
- Ampule
- Carton
- Auto Injector
- and More
ECL Questions?
Not sure of what you need for your application ? One of our packaging specialists will be glad to help.
Why Choose CCL Healthcare for Encapsulated Leaflets
Choose a partner with deep industry expertise and proven global capabilities:
- We manufacture in dozens of dedicated cGMP compliant healthcare facilities, providing regional access and global consistency
- Every product is vision-verified for 100% accuracy and documented for full traceability
- Labels are produced in temperature- and humidity-controlled environments to maintain quality
- Teams follow strict SOPs and ISO standards to meet the demands of regulated industries
- Our engineers collaborate directly with your team to create innovative, compliant labeling solutions
- We deliver forward-thinking solutions by investing in advanced ECL products backed by smart label technology
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Streamline Complex Labeling With a Single, Secure Solution
Encapsulated leaflet labels deliver the space-saving flexibility and regulatory compliance your pharmaceutical packaging requires. Whether you’re navigating clinical trials or high-volume production, CCL Healthcare has the global support, advanced capabilities and industry-leading experience to help you find the right solution for your packaging needs.Â
Start simplifying your labeling strategy. Explore our full expanded content label product range, or contact us to request a tailored quote.
